Solters and Roskin · Public domain

Gilda Radner was one of the seven original cast members of Saturday Night Live, creating enduring characters like Emily Litella and Roseanne Roseannadanna and winning an Emmy for her performances before leaving in 1980. She continued acting on stage and screen, including three films with her husband Gene Wilder, and after being diagnosed with ovarian cancer in 1986, wrote candidly about her illness in the memoir It's Always Something before her death in 1989 — work that inspired ongoing cancer support programs founded in her name.