Keith Middlebrook at https://www.flickr.com/photos/19786782@N07/ · CC BY-SA 3.0

Jeremy Piven made Ari Gold, the profanely persuasive Hollywood agent of Entourage, into a career-defining role that won him a Golden Globe and three consecutive Emmy Awards. He went on to headline the British period drama Mr Selfridge as the department store's American founder, and earlier played Spence Kovak opposite Ellen DeGeneres in her sitcom Ellen.