Harald Krichel · CC BY-SA 4.0

Bialik has spent three decades building an unusually specific niche in American television, starring as the title character of Blossom as a teenager, then returning in her thirties to play physicist Amy Farrah Fowler on The Big Bang Theory, a role that brought four Emmy nominations and two Critics' Choice wins. She later shared hosting duties on Jeopardy! with Ken Jennings, a rare instance of an actor stepping behind the lectern of American television's most enduring quiz show.