Unknown author · CC BY 4.0

Worked out how aspirin actually relieves pain and inflammation, showing it blocks the body's production of prostaglandins — a discovery that reshaped drug research well beyond aspirin itself, contributing to the later development of ACE inhibitors and other treatments for heart and blood vessel disease. He shared the 1982 Nobel Prize in Physiology or Medicine with Sune Bergström and Bengt Samuelsson for the work on prostaglandins.